孙崇秀
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发布人:gnjyadmin  发布时间:2016-09-26   动态浏览次数:10



简介:

  孙崇秀,女,江苏扬州人,教授,博士生导师。于南京大学生物化学与分子生物学专业获博士学位后,分别在美国哈佛医学院和加州大学从事心血管疾病与代谢相关研究。2015年受聘于南京医科大学,现主持国家自然科学基金面上项目1项。在SCI收录期刊发表文章近20篇,代表性论文发表在Circulation、Circ Res、Nat Med等专业杂志。

专业方向:

生物化学与分子生物学

科研方向:

内皮功能失调与动脉粥样硬化。

主要学术兼职:

江苏省细胞与发育生物学学会理事

近年承担课题情况:

内皮IRF-1参与动脉粥样硬化的机制,国家自然科学基金面上项目,主持

近5年代表性论文:

1.Sun C, Simon SI, Foster GA, Radecke CE, Hwang HV, Zhang X, Hammock BD, Chiamvimonvat N, Knowlton AA. 11,12-Epoxyecosatrienoic acids mitigate endothelial dysfunction associated with estrogen loss and aging: Role of Membrane depolarization. J Mol Cell Cardiol.2016 May;94:180-8.PMID:27079253 (IF=4.7)

2.Wang J#,SunC#, Gerdes N, Liu C, Liao M, Liu J,ShiMA, He A, Zhou Y, Sukhova GK, Chen H, Cheng XW, Kuzuya M, Murohara T, Zhang J, Cheng X, Jiang M, Shull GE, Rogers S, Yang CL, Ke Q, Jelen S, Bindels R, Ellison DH, Jarolim P,LibbyP,ShiGP.Interleukin 18 function in atherosclerosis is mediated by the interleukin 18 receptor and the Na-Cl co-transporter.Nat Med. 2015 Jul;21(7):820-6. PMID: 26481668 (#并列一作, IF=28.1))

3.Sun C, Rigor RR, Konia T, Wu MH and Yuan SY. ADAM15 deficiency attenuates pulmonary hyperpermeability and acute lung injury in lipopolysaccharide-treated mice. Am J PhysiolLung Cell Mol Physiol. 2013 Feb 1;304(3):L135-42. PMID: 23161886(IF=4.0)

4.Sun C, Wu MH, Lee ES, and Yuan S. ADAM15 contributes to atherosclerosis by mediating endothelial barrier dysfunction via Src family kinase activity. ArteriosclerThrombVasc Biol. 2012 Oct;32(10):2444-51. PMID: 22904271(IF=6.1)

5.Sun C, Alkhoury K, Wang Y, Foster GA, Radecke CE, Tam K, Edwards CM, Facciotti MT, Armstrong EJ, Knowlton AA, Newman JW, Passerini AG, Simon SI. IRF-1 and miRNA126 Modulate VCAM-1 Expression in Response to a High Fat Meal.Circ Res.2012 Sep 28;111(8):1054-64. PMID: 22874466(IF=11.9)

6.Sun C, Wu MH, Yuan SY. nmMLCK deficiency ameliorates atherosclerosis in ApoE-deficient mice via reduced endothelial barrier dysfunction and monocyte migration. Circulation. 2011 Jul 5;124(1):48-57. PMID: 21670231(IF=14.7)